News

Markley Silva Oliveira Junior, Laura Reiche, Emerson Daniele, Ines Kortebi, Maryam Faiz, Patrick Küry.

Star power: harnessing the reactive astrocyte response to promote remyelination in multiple sclerosis.

Neural Regen Res. 2024 Mar;19(3):578-582. doi: 10.4103/1673-5374.380879. PubMed ID: 37721287

Further Information:

Joel Gruchot, Isabel Lewen, Michael Dietrich, Laura Reiche, Mustafa Sindi, Christina Hecker, Felisa Herrero, Benjamin Charvet, Ulrike Weber-Stadlbauer, Hans-Peter Hartung, Philipp Albrecht, Hervé Perron, Urs Meyer, Patrick Küry.

Transgenic expression of the HERV-W envelope protein leads to polarized glial cell populations and a neurodegenerative environment.

Proc Natl Acad Sci U S A. 2023 Sep 19;120(38):e2308187120. doi: 10.1073/pnas.2308187120. Epub 2023 Sep 11. PubMed ID: 37695891

Further Information:

Lisa Nguyen, Leonie Thewes, Michelle Westerhoff, Wasco Wruck, Andreas S Reichert, Carsten Berndt, James Adjaye.

JNK Signalling Regulates Self-Renewal of Proliferative Urine-Derived Renal Progenitor Cells via Inhibition of Ferroptosis.

Cells. 2023 Sep 2;12(17):2197. doi: 10.3390/cells12172197. PubMed ID: 37681928

Further Information:

Gebhard Stopper, Laura C Caudal, Phillip Rieder, Davide Gobbo, Laura Stopper, Lisa Felix, Katharina Everaerts, Xianshu Bai, Christine R Rose, Anja Scheller, Frank Kirchhoff.

Novel algorithms for improved detection and analysis of fluorescent signal fluctuations.

2023 Nov;475(11):1283-1300. doi: 10.1007/s00424-023-02855-3. Epub 2023 Sep 13. PubMed ID: 37700120 PubMed ID: 37700120

Further Information:

Mustafa Sindi, Christina Hecker, Andrea Issberner, Tobias Ruck, Sven G Meuth, Philipp Albrecht, Michael Dietrich.

S1PR-1/5 modulator RP-101074 shows beneficial effects in a model of central nervous system degeneration.

Front Immunol. 2023 Aug 9;14:1234984. doi: 10.3389/fimmu.2023.1234984. eCollection 2023. PubMed ID: 37638037

Further Information:

Luisa Werner, Michael Gliem, Nicole Rychlik, Goran Pavic, Laura Reiche, Frank Kirchhoff, Markley Silva Oliveira Junior, Joel Gruchot, Sven G Meuth, Patrick Küry, Peter Göttle.

A Novel Ex Vivo Model to Study Therapeutic Treatments for Myelin Repair following Ischemic Damage.

Int J Mol Sci. 2023 Jun 30;24(13):10972. doi: 10.3390/ijms241310972. PubMed ID: 37446147

Further Information:

Nils Pape, Christine R Rose, 

Activation of TRPV4 channels promotes the loss of cellular ATP in organotypic slices of the mouse neocortex exposed to chemical ischemia.

Int J Mol Sci. 2023 Jun 30;24(13):10972.doi: 10.3390/ijms241310972. PubMed ID: 37446147

Further Information:

Graduated April 28, 2023

Lisa Maria Metz, Tobias Feige, Larissa de Biasi, Agnes Ehrenberg, Joscha Mulorz, Laura Mara Toska, Friedrich Reusswig, Christine Quast, Norbert Gerdes, Malte Kelm, Hubert Schelzig, Margitta Elvers.

Platelet pannexin-1 channels modulate neutrophil activation and migration but not the progression of abdominal aortic aneurysm.

Front Mol Biosci. 2023 Mar 6:10:1111108. doi: 10.3389/fmolb.2023.1111108. eCollection 2023. PubMed ID: 36950521

Further Information: